Searchable abstracts of presentations at key conferences in endocrinology

ea0090p9 | Adrenal and Cardiovascular Endocrinology | ECE2023

Determination of dexamethasone level by liquid chromatography with tandem mass spectrometry after low-dose dexamethasone suppression test

Brutvan Tomas , Kotasova Marcela , Sevcik Jan , Springer Drahomira , Ježkova Jana

Introduction: Low-dose dexamethasone suppression test is used to screen for excess cortisol production (Cushing’s syndrome). It is recommended to use cut-off for suppression of serum cortisol (SC) < 50 nmol/l after 1 mg dexamehason suppression test (DST). Plasma dexamethasone levels are affected by many factors resulting in lower test specificity. Simultaneous analysis of dexamethasone and cortisol levels can improve diagnostic accuracy of DST. We used cut-off level o...

ea0090p212 | Thyroid | ECE2023

Iodine supply and thyroid status of women with gestational diabetes mellitus and their impact on birth outcomes

Vitkova Hana , Kratky Jan , Brutvan Tomas , Jiskra Jan , Anderlova Katerina , Radimerska Veronika , Bilek Radovan , Springer Drahomira , Votava Felix , Potlukova Eliska

Introduction: Urinary iodine concentration (UIC) and neonatal thyroid stimulating hormone (neoTSH) concentrations can reflect changes in iodine status and serve as a sensitive marker of iodine intake in pregnancy. As gestational diabetes mellitus (GDM) requires some diet modification, the study aimed to map the situation of iodine intake in women with GDM compared to healthy pregnant women and explore a relationship to thyroid function.Methods: In the tw...